In a world where laughter often serves as the best medicine, Nick and Linda Manno from Jamestown embody this sentiment ...

The Breast Health Center at ECMC officially opened its doors in Buffalo's Delevan-Grider neighborhood on Monday.

The New York State Department of Transportation's largest engineering project in Western New York is underway on the I-86 bridge in Chautauqua County, with a price tag of at least $78 million.

An effort is underway to make it safer for cyclists. New bike lanes have been installed along a section of Sheridan Drive in ...

A massive wildfire is churning through Los Padres National Forest in central California, threatening hundreds of homes after ...

Wildfire smoke from Canada is over our region. Pollutants will be elevated across the region with an Air Quality Alert in ...

After sitting empty for more than a decade, Ellicottville’s iconic 1887 Building is about to get a second chance.

Much like Sunday's training camp practice, Monday's once again revolved around Buffalo Bills running back James Cook and his "business" decision to not practice with the team.

The Divans were described as generous and humble individuals who were pillars of the Western New York Indian community.

A member of the New York State Army National Guard was arrested for attempting to smuggle contraband into the Collins Correctional Facility.

The vast majority of U.S. adults are at least somewhat stressed about the cost of groceries, a new poll finds.

Amherst Police announced a motorcyclist was killed after a crash on Main Street on Friday morning. The crash, which involved ...