Introduction SLE is a chronic autoimmune disease characterised by multisystem involvement and fluctuating clinical course, ...

Background Aortogenic stroke is an important subtype of embolic strokes, yet lacks a diagnostic method for proactive ...

This valuable study identifies a brown adipose tissue-specific heat shock factor 1-alcohol dehydrogenase 5 (ADH5) molecular cascade as a regulator of systemic aging, showing that ADH5 deficiency ...

Myc dysregulation in activated macrophages impairs antioxidant defenses, locking them in a vicious cycle that amplifies type I interferon signaling, driving hyperinflammation and immunosuppression.