Introduction SLE is a chronic autoimmune disease characterised by multisystem involvement and fluctuating clinical course, ...
Malaria treatment failures associated with reduced efficacy of chloroquine (CQ) and amodiaquine (AQ) antimalarial drugs ...
This valuable study identifies a brown adipose tissue-specific heat shock factor 1-alcohol dehydrogenase 5 (ADH5) molecular cascade as a regulator of systemic aging, showing that ADH5 deficiency ...
Myc dysregulation in activated macrophages impairs antioxidant defenses, locking them in a vicious cycle that amplifies type I interferon signaling, driving hyperinflammation and immunosuppression.
Transition between cell states of sensitivity reveals molecular vulnerability of drug-tolerant cells
Cancer cells evade apoptosis by transitioning between cell states of drug-sensitivity. Necroptosis vulnerability state was ...
Background Aortogenic stroke is an important subtype of embolic strokes, yet lacks a diagnostic method for proactive ...
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