The antibody response and the complement system are major effector arms of the immune system. Both have been involved in a plethora of pathological conditions – including autoimmunity, allergy, ...
Global understanding of complement has shifted and developed since the 21st century: from our idea of a blood-based antibiotic system to a global regulator of immunity and tissue homeostasis. Recent ...
The founder of InflaRX discusses lessons learned during the COVID-19 pandemic and how they’re being applied in a ...
Nipocalimab might lower the concentration of anti-acetylcholine receptor antibodies in people with generalized myasthenia gravis, a study shows. PHOENIX, Arizona—Nipocalimab might lower the ...
Newcastle researchers have revealed the first treatment to target the underlying cause of a rare kidney condition called "C3G ...
Complement 3 glomerulopathy (C3 glomerulopathy) is a very rare kidney disease. Those diagnosed with it have one of two forms of this disease: dense deposit disease (DDD) or C3 glomerulonephritis (C3GN ...
These findings suggest complement protein levels may be an important biomarker for type 1 diabetes. Disruption of the complement system appears to precede the onset of islet autoimmunity (IA), making ...