Edited by Scott Hultgren, Washington University in St. Louis School of Medicine, St. Louis, MO; received March 7, 2024; accepted January 27, 2025 ...

Rapid pathogen detection is crucial for effective disease management, particularly in bloodstream infections. Current molecular diagnostics often require nucleic acid preamplification, adding time and ...

Contributed by Chi-Ming Che; received October 6, 2023; accepted April 27, 2024; reviewed by Harry B. Gray and Yi Lu ...

Contributed by Ian J. Bateman; received April 20, 2024; accepted October 3, 2024; reviewed by Roy Brouwer, Catherine L. Kling, and Marije Schaafsma This contribution is part of the special series of ...

We show that for thousands of years, humans have concentrated in a surprisingly narrow subset of Earth’s available climates, characterized by mean annual temperatures around ∼13 °C. This distribution ...

Edited by Danielle Basset, University of Pennsylvania, Philadelphia, PA; received May 2, 2024; accepted January 28, 2025, by Editorial Board Member Elizabeth A. Buffalo ...

Self-reproduction is one of the most fundamental features of natural life. This study introduces a biochemistry-free method for creating self-reproducing polymeric vesicles. In this process, ...

Edited by Michael S. Diamond, Washington University in St. Louis School of Medicine, St. Louis, MO; received August 17, 2023; accepted March 20, 2024 by Editorial Board Member Katherine A. Fitzgerald ...

The extent and impact of Early Medieval population movements on the establishment of trade and cultural networks across the North Sea have been the subject of debate for centuries. Analyzing ancient ...

We characterized the human body’s immune cells distribution and provided its total weight. Our findings show that an average individual’s immune system consists of approximately 1.8 trillion cells, ...

In contrast to most crops, Vitis vinifera benefited little from classical breeding due to their heterozygosis. Strikingly, the main cultivated grape varieties that we see today have remained the same ...

Healthy brain function requires a delicate balance of neural excitation (E) and inhibition (I). In animals, this balance—the E/I ratio—is known to decrease with the maturation of inhibitory circuitry ...