This valuable study analyzes aging-related chromatin changes through the lens of intra-chromosomal gene correlation length, which is a novel computational metric that captures spatial correlations in ...

High background noise in RNA samples can impact read accuracy and increase sequencing costs. Optimizing sample quality enables better microRNA mapping and more reliable insights in transcriptomics and ...

This article explores how to generate high-quality transcriptomics data by optimizing each step, from experimental design and RNA extraction to library preparation sequencing and data analysis, to ...

The world of cells is surprisingly noisy. Each cell carries unique genetic information, but when we try to measure cellular activity, signals can be lost or blurred, and differences between ...

BACKGROUND: Alternative splicing plays crucial roles in normal heart development and cardiac disease by influencing protein-coding sequences, functional domains, and molecular networks. However, a ...

Essentially all cells in an organism's body have the same genetic blueprint, or genome, but the set of genes that are actively expressed at any given time in a cell determines what type of cell it ...

Live-seq brings longitudinal, non-destructive cell sequencing to every lab, revealing new insights into cellular behavior ...

Through a comprehensive approach combining transcriptomic profiling, histological analysis, and functional validation in ...

Northwestern University has announced a new method for detecting RNA modification patterns to enhance early colon cancer ...