Scientists have uncovered how a newly discovered gene, NEK1, in which mutations have been linked to ALS cases, disrupts the function of the motor neuron and causes it to degenerate and die. The viral ...
A study has described how a gene mutation linked to amyotrophic lateral sclerosis (ALS) disrupts the stability of neurons and “chokes off” their nuclei, impairing their function. The research, ...
Pictured are nuclei of induced pluripotent stem cell (iPSC)-derived motor neurons stained for contrast. The nucleus on the left has been treated with DMSO (control) and appears mostly blue. The ...
Scientists have discovered a new kind of synapse in the tiny hairs on the surface of neurons. The commonly overlooked protrusions called primary cilia contain special junctions that act as a shortcut ...
Researchers have uncovered a synapse on neurons’ tiny hair-like structures, which may facilitate long-term changes to genomic information in the nucleus. A new study from the Howard Hughes Medical ...
When you interact with the world around you, your experiences are recorded as changes in the connection strengths between neurons in your brain. This process, called synaptic plasticity, alters how ...
Scientists at HHMI's Janelia Research Campus have discovered a new kind of synapse in the tiny hairs on the surface of neurons. The commonly overlooked protrusions called primary cilia contain special ...