Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium ...
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Mechanical model reveals how prions trigger a domino effect to spread misfolded proteins
Prions, mysterious shape-shifting proteins, can lead to brain disorders such as Creutzfeldt-Jakob disease in humans and bovine spongiform encephalopathy, "mad cow disease" in cattle, yet they can also ...
Duchenne muscular dystrophy (DMD) is a rare but devastating genetic disorder that causes muscle loss and physical impairments. Researchers have shown in a mouse study that the powerful gene editing ...
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