Ishikawa, Japan - The correct functioning of our cells rests upon the precise orchestration of many complex processes and organelles. Lysosomes—vital cell organelles—are enzyme-filled subunits found ...

In a rare disease called mucolipidosis type II, people's hearts and abdomens swell, and their bones grow malformed. A lysosomal storage disorder, mucolipidosis type II causes edema of the internal ...

Lysosomes, often reductively referred to as the "garbage disposals" of cells, play a pivotal role in our cells’ digestive systems by getting rid of unwanted materials. Now in a groundbreaking study, ...

Organelle remodeling is critical for cellular homeostasis, but host factors that control organelle function during microbial infection remain largely uncharacterized. Here, a genome-scale CRISPR/Cas9 ...

Lysosomes play an important role in cells and tissues, controlling not only the degradation of substances but also cell division and growth. A team led by Professor Volker Haucke and Dr. Michael Ebner ...

Researchers at the National Institutes of Health (NIH) have discovered a biological pathway that the novel coronavirus appears to use to hijack and exit cells as it spreads through the body. A better ...

In diseases such as hypertension, aging, atherosclerosis, diabetes and chronic kidney disease, arterial calcification and stiffening of the elastic layer of the arterial wall are almost always present ...