This section introduces the mathematical notation used throughout this chapter to describe the mixed linear model. You should be familiar with basic matrix algebra (refer to Searle 1982). A more ...

Linear mixed models (LMMs) serve as a versatile statistical framework, combining fixed effects that capture the overall trends with random effects that account for variability across subjects, ...

This section provides an overview of a likelihood-based approach to general linear mixed models. This approach simplifies and unifies many common statistical analyses, including those involving ...